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June W. Lau (Fed)

Physicist and Laboratory Data Science Team Lead

While AI's impact is undeniable, the reach of AI into the disciplinary depths of scientific domains and subdomains has been haltingly slow and incremental. For the most part, scientific institutions are not enjoying the pan-laboratory boom that is more commonplace, for instance, in our social spheres. The reasons for the unyielding nature of research are many-fold, but perhaps the most salient reason is the lack of a common standard, often even within a single scientific field.

A reasonable step towards machine-actionable scientific research data is described by the FAIR (findable, accessible, interoperable, and reusable) framework. Reducing this framework to practice has been, and continues to be, a long and challenging road. While at NIST, my research team and I built the first laboratory information management system (LIMS) to automatically manage, curate, and tag electron microscopy datasets from a research microscopy facility. Doing so has enabled data reuse from precious tax-supported resources. Following this success, we are broadening this vision of machine-actionable scientific research data to all of NIST.

Recent events had given us incredible opportunities to showcase our innovations in measurement science that will directly benefit our nation's manufacturing engine. Our research workflows are baked into the data curation processes where a secure and auditable pipeline takes research data from the point of creation to the end publications and data products. We are AI-ready!

Where this could lead is a new paradigm for R&D. If we succeed in de-siloing discipline-specific research, we will enhance research partnerships and help researchers achieve results far faster because the shared knowledge can be made persistent and discoverable. My work motivates me because each day delayed is another day lost for scientific breakthroughs that might solve some of humanity's most pressing challenges.

 

Awards

2020 Microscopy Today Innovation Award
Issued by Microscopy Today · Aug 2020
The stroboscopic TEM (jointly held by Euclid tech Labs, BNL, and NIST), wins the Microscopy Today Innovation Award.
 

R&D 100 Award
Issued by R&D World · Oct 2019
Associated with National Institute of Standards and Technology (NIST)
2019 R&D100 Award for "Affordable Laser-free Retrofittable Stroboscopic Solution for Ultra-fast Electron Microscopy"
https://www.rdworldonline.com/2019-rd-100-award-winners-unveiled/

 

Patents 

Radio-frequency (RF) transmission systems, devices, and methods for in situ transmission electron microscopy. 
US 11,069,507 · Issued Jul 20, 2021US 11,069,507 · Issued Jul 20, 2021 

Ultra-broadband continuously tunable electron beam pulser.
US 10,319,556 · Issued Jun 11, 2019US 10,319,556 · Issued Jun 11, 2019 

Apparatus for GHz rate high duty cycle pulsing and manipulation of low and medium energy DC electron beams.
US 9,697,982 · Issued Jul 4, 2017

 
 

Publications

Advancing Measurement Science for Microelectronics: CHIPS R&D Metrology Program

Author(s)
Marla L. Dowell, Hannah Brown, Gretchen Greene, Paul D. Hale, Brian Hoskins, Sarah Hughes, Bob R. Keller, R Joseph Kline, June W. Lau, Jeff Shainline
The CHIPS and Science Act of 2022 called for NIST to "carry out a microelectronics research program to enable advances and breakthroughs....that will accelerate

A Roadmap for LIMS at NIST Material Measurement Laboratory

Author(s)
Gretchen Greene, Jared Ragland, Zachary Trautt, June W. Lau, Raymond Plante, Joshua Taillon, Adam Abel Creuziger, Chandler A. Becker, Joe Bennett, Niksa Blonder, Lisa Borsuk, Carelyn E. Campbell, Adam Friss, Lucas Hale, Michael Halter, Robert Hanisch, Gary R. Hardin, Lyle E. Levine, Samantha Maragh, Sierra Miller, Chris Muzny, Marcus William Newrock, John Perkins, Anne L. Plant, Bruce D. Ravel, David J. Ross, John Henry J. Scott, Christopher Szakal, Alessandro Tona, Peter Vallone
Instrumentation generates data faster and in higher quantity than ever before, and interlaboratory research is in historic demand domestically and
Created October 9, 2019, Updated April 24, 2025