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Health / Clinical diagnostics

Medical imaging

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Displaying 201 - 225 of 229

Monitoring Photothermally Excited Nanoparticles via Multimodal Microscopy

May 19, 2010
Author(s)
Matthew L. Clarke, Shin G. Chou, Jeeseong Hwang
Generation of heat using optically excited nanoparticles can be beneficial or detrimental depending on the application. Therefore, clinically applicable studies are being pursued in an effort to achieve safe practices of nanoparticle-induced hyperthermia

Fluorinated Copolymer Nanoparticles for Multimodal Imaging Applications

February 18, 2010
Author(s)
Mark M. Bailey, Christine M. Mahoney, Elodie Dempah, Jeffrey M. Davis, Matthew Becker, Supang Khondee, Eric J. Munson, Cory J. Berkland
Nanomaterials have emerged as valuable tools in biomedical imaging techniques, such as magnetic resonance imaging (MRI), fluorescence, positron emission tomography (PET), and others. Some have been designed to serve as multimodal imaging agents, combining

Low-Cost, High-Throughput, Automated Counting of Bacterial Colonies

January 5, 2010
Author(s)
Matthew L. Clarke, Robert L. Burton, A. N. Hill, Maritoni A. Litorja, Moon H. Nahm, Jeeseong Hwang
Research involving bacterial pathogens often requires enumeration of bacteria colonies. Here we present a low-cost, high-throughput colony counting system consisting of colony counting software and a consumer-grade digital camera or document scanner. We

A Quality Pre-Processor for Biological Cell Images

November 30, 2009
Author(s)
Adele P. Peskin, Karen Kafadar, Alden A. Dima
We have developed a method to rapidly test the quality of a biological image, to identify appropriate segmentation methods, if any, that will render high quality segmentations for the cells within that image. The key contribution is the development of a

Robust Volume Calculations of Tumors of Various Sizes

July 13, 2009
Author(s)
Adele P. Peskin, Karen Kafadar, A.M. Santos, Gillian Haemer
Many advances in medicine today require the accurate reading of computerized tomographic (CT) images of the body. Tumors in the lung, for example, are classified according to their detected growth, i.e. change in volume, over a period of time. CT data are

Synthetic Lung Tumor Data Sets for Comparison of Volumetric Algorithms

July 13, 2009
Author(s)
Adele P. Peskin, Alden A. Dima, Javier Bernal, David E. Gilsinn, Karen Kafadar
The change in pulmonary nodules over time is an important indicator of malignant tumors. It is therefore important to be able to measure change in the size of tumors from computed tomography (CT) data taken at different times and on potentially different

Pulse shaping for background free broadband CARS

March 16, 2009
Author(s)
Young Jong Lee, Marcus T. Cicerone
We demonstrate that pulse shaping of a probe pulse can suppress the nonresonant background (NRB) contribution and retrieve resonant Raman signal efficiently in broadband coherent anti-Stokes Raman scattering (CARS) spectrum. A pulse shaper prepares a probe

Surface plasmon resonance imaging of cells and surface-associated fibronectin

February 26, 2009
Author(s)
Alexander W. Peterson, Michael W. Halter, Alessandro Tona, Kiran Bhadriraju, Anne L. Plant
Background A critical challenge in cell biology is quantifying the interactions of cells with their extracellular matrix (ECM) environment and the active remodeling by cells of their ECM. Fluorescence microscopy is a commonly employed technique for

Micro-engineered local field control for high-sensitivity multi-spectral MRI

June 19, 2008
Author(s)
Gary Zabow, Stephen Dodd, John M. Moreland, Alan P. Koretsky
In recent years, biotechnology and biomedical research have benefited from the introduction of a variety of specialized nanoparticles whose well-defined, optically distinguishable signatures enable simultaneous tracking of numerous biological indicators